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Critical regulation of early Th17 cell differentiation by IL-1 signaling

Th17 cells have been recently discovered in both mouse and human. Although IL-1 has been shown to be important in human Th17 cell differentiation with little knowledge of the underlying mechanism, its function in mouse is less clear. Here we show that IL-1R1 expression in T cells, which was induced...

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Bibliografiske detaljer
Main Authors: Chung, Yeonseok, Chang, Seon Hee, Martinez, Gustavo J., Yang, Xuexian O., Nurieva, Roza, Kang, Hong Soon, Ma, Li, Watowich, Stephanie S., Jetten, Anton, Tian, Qiang, Dong, Chen
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705871/
https://ncbi.nlm.nih.gov/pubmed/19362022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.02.007
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