Transcription of Il17 and Il17f is controlled by conserved non-coding sequence (CNS) 2

T helper 17 (Th17) cells specifically transcribe the Il17 and Il17f genes, which are localized in the same chromosome region, but the underlying mechanism is unclear. Here, we report a cis element that we previously named conserved noncoding sequence 2 (CNS2), physically interacted with both Il17 an...

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Autors principals: Wang, Xiaohu, Zhang, Yibing, Yang, Xuexian O., Nurieva, Roza I., Chang, Seon Hee, Ojeda, Sandra S., Kang, Hong S., Schluns, Kimberly S., Gui, Jianfang, Jetten, Anton M., Dong, Chen
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270375/
https://ncbi.nlm.nih.gov/pubmed/22244845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.10.019
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