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The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation
Yes-associated protein (YAP) is a potent transcription coactivator acting via binding to the TEAD transcription factor, and plays a critical role in organ size regulation. YAP is phosphorylated and inhibited by the Lats kinase, a key component of the Hippo tumor suppressor pathway. Elevated YAP prot...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Cold Spring Harbor Laboratory Press
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878649/ https://ncbi.nlm.nih.gov/pubmed/20516196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1903310 |
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