The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

Yes-associated protein (YAP) is a potent transcription coactivator acting via binding to the TEAD transcription factor, and plays a critical role in organ size regulation. YAP is phosphorylated and inhibited by the Lats kinase, a key component of the Hippo tumor suppressor pathway. Elevated YAP prot...

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Autori principali: Lian, Ian, Kim, Joungmok, Okazawa, Hideki, Zhao, Jiagang, Zhao, Bin, Yu, Jindan, Chinnaiyan, Arul, Israel, Mason A., Goldstein, Lawrence S.B., Abujarour, Ramzey, Ding, Sheng, Guan, Kun-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878649/
https://ncbi.nlm.nih.gov/pubmed/20516196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1903310
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