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TEAD mediates YAP-dependent gene induction and growth control
The YAP transcription coactivator has been implicated as an oncogene and is amplified in human cancers. Recent studies have established that YAP is phosphorylated and inhibited by the Hippo tumor suppressor pathway. Here we demonstrate that the TEAD family transcription factors are essential in medi...
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| Autors principals: | , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2492741/ https://ncbi.nlm.nih.gov/pubmed/18579750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1664408 |
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