TEAD mediates YAP-dependent gene induction and growth control

The YAP transcription coactivator has been implicated as an oncogene and is amplified in human cancers. Recent studies have established that YAP is phosphorylated and inhibited by the Hippo tumor suppressor pathway. Here we demonstrate that the TEAD family transcription factors are essential in medi...

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Autores principales: Zhao, Bin, Ye, Xin, Yu, Jindan, Li, Li, Li, Weiquan, Li, Siming, Yu, Jianjun, Lin, Jiandie D., Wang, Cun-Yu, Chinnaiyan, Arul M., Lai, Zhi-Chun, Guan, Kun-Liang
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492741/
https://ncbi.nlm.nih.gov/pubmed/18579750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1664408
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