Identification and Characterization of Murine Mitochondria-associated Neutral Sphingomyelinase (MA-nSMase), the Mammalian Sphingomyelin Phosphodiesterase 5

Sphingolipids play important roles in regulating cellular responses. Although mitochondria contain sphingolipids, direct regulation of their levels in mitochondria or mitochondria-associated membranes is mostly unclear. Neutral SMase (N-SMase) isoforms, which catalyze hydrolysis of sphingomyelin (SM...

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Detalles Bibliográficos
Main Authors: Wu, Bill X., Rajagopalan, Vinodh, Roddy, Patrick L., Clarke, Christopher J., Hannun, Yusuf A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Lipids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878561/
https://ncbi.nlm.nih.gov/pubmed/20378533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102988
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