Over-expression of Runx1 transcription factor impairs the development of thymocytes from the double-negative to double-positive stages

Runx1 transcription factor is highly expressed at a CD4/CD8-double-negative (DN) stage of thymocyte development but is down-regulated when cells proceed to the double-positive (DP) stage. In the present study, we examined whether the down-regulation of Runx1 is necessary for thymocyte differentiatio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wong, Won F, Nakazato, Megumi, Watanabe, Toshio, Kohu, Kazuyoshi, Ogata, Takehiro, Yoshida, Naomi, Sotomaru, Yusuke, Ito, Mamoru, Araki, Kimi, Telfer, Janice, Fukumoto, Manabu, Suzuki, Daisuke, Sato, Takehito, Hozumi, Katsuto, Habu, Sonoko, Satake, Masanobu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2010
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878468/
https://ncbi.nlm.nih.gov/pubmed/20102410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03230.x
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