Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain

BACKGROUND: An alarming portion of patients develop persistent or chronic pain following surgical procedures, but the mechanisms underlying the transition from acute to chronic pain states are not fully understood. In general, endocannabinoids (ECBs) inhibit nociceptive processing by stimulating can...

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Main Authors: Alkaitis, Matthew S., Solorzano, Carlos, Landry, Russell P., Piomelli, Daniele, DeLeo, Joyce A., Romero-Sandoval, E. Alfonso
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878341/
https://ncbi.nlm.nih.gov/pubmed/20531936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010891
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