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Spinal cannabinoid receptor type 2 agonist reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatases in a rat model of neuropathic pain

Peripheral nerve injury generally results in spinal neuronal and glial plastic changes associated with chronic behavioral hypersensitivity. Spinal mitogen-activated protein kinases (MAPKs), e.g., p38 or extracellular signal-regulated kinases (ERKs), are instrumental in the development of chronic all...

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Hlavní autoři: Landry, Russell P., Martinez, Elena, DeLeo, Joyce A., Romero-Sandoval, E. Alfonso
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438333/
https://ncbi.nlm.nih.gov/pubmed/22901764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2012.05.013
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