Evidence for a Role of Endocannabinoids, Astrocytes and p38 Phosphorylation in the Resolution of Postoperative Pain

BACKGROUND: An alarming portion of patients develop persistent or chronic pain following surgical procedures, but the mechanisms underlying the transition from acute to chronic pain states are not fully understood. In general, endocannabinoids (ECBs) inhibit nociceptive processing by stimulating can...

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Detalhes bibliográficos
Main Authors: Alkaitis, Matthew S., Solorzano, Carlos, Landry, Russell P., Piomelli, Daniele, DeLeo, Joyce A., Romero-Sandoval, E. Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878341/
https://ncbi.nlm.nih.gov/pubmed/20531936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010891
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