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Merotelic attachments and non-homologous end joining are the basis of chromosomal instability
Although the large majority of solid tumors show a combination of mitotic spindle defects and chromosomal instability, little is known about the mechanisms that govern the initial steps in tumorigenesis. The recent report of spindle-induced DNA damage provides evidence for a single mechanism respons...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878296/ https://ncbi.nlm.nih.gov/pubmed/20478024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-5-13 |
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