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Centromere fission, not telomere erosion, triggers chromosomal instability in human carcinomas

The majority of sporadic carcinomas suffer from a kind of genetic instability in which chromosome number changes occur together with segmental defects. This means that changes involving intact chromosomes accompany breakage-induced alterations. Whereas the causes of aneuploidy are described in detai...

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Detalhes bibliográficos
Main Authors: Martínez-A, Carlos, van Wely, Karel H.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106440/
https://ncbi.nlm.nih.gov/pubmed/21478459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr069
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