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Telomere loss as a mechanism for chromosome instability in human cancer

Cancer cells commonly have a high rate of telomere loss, even when expressing telomerase, contributing to chromosome instability and tumor cell progression. This review addresses the hypothesis that this high rate of telomere loss results from a combination of four factors. The first factor is an in...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile nagusia: Murnane, John. P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967490/
https://ncbi.nlm.nih.gov/pubmed/20484032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4357
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