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The Relationship Between Spontaneous Telomere Loss and Chromosome Instability in a Human Tumor Cell Line

Chromosome instability plays an important role in cancer by promoting the alterations in the genome required for tumor cell progression. The loss of telomeres that protect the ends of chromosomes and prevent chromosome fusion has been proposed as one mechanism for chromosome instability in cancer ce...

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Detalhes bibliográficos
Main Authors: Fouladi, Bijan, Sabatier, Laure, Miller, Douglas, Pottier, Geraldine, Murnane, John P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature America, Inc. 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508089/
https://ncbi.nlm.nih.gov/pubmed/11228547
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