DNA Amplification by Breakage/Fusion/Bridge Cycles Initiated by Spontaneous Telomere Loss in a Human Cancer Cell Line

The development of genomic instability is an important step in generating the multiple genetic changes required for cancer. One consequence of genomic instability is the overexpression of oncogenes due to gene amplification. One mechanism for gene amplification is the breakage/fusion/bridge (B/F/B)...

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Detaylı Bibliyografya
Asıl Yazarlar: Lo, Anthony W I, Sabatier, Laure, Fouladi, Bijan, Pottier, Géraldine, Ricoul, Michelle, Murnane, John P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2002
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1503667/
https://ncbi.nlm.nih.gov/pubmed/12407447
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