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Telomeres, chromosome instability and cancer

Telomeres are composed of repetitive G-rich sequence and an abundance of associated proteins that together form a dynamic cap that protects chromosome ends and allows them to be distinguished from deleterious DSBs. Telomere-associated proteins also function to regulate telomerase, the ribonucleoprto...

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Detalles Bibliográficos
Main Authors: Bailey, Susan M., Murnane, John P.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2006
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1458522/
https://ncbi.nlm.nih.gov/pubmed/16682448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl303
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