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ATM limits incorrect end utilization during non-homologous end joining of multiple chromosome breaks.
Chromosome rearrangements can form when incorrect ends are matched during end joining (EJ) repair of multiple chromosomal double-strand breaks (DSBs). We tested whether the ATM kinase limits chromosome rearrangements via suppressing incorrect end utilization during EJ repair of multiple DSBs. For th...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science (PLoS)
2010-11-01
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Colecção: | PLoS Genetics |
Acesso em linha: | http://europepmc.org/articles/PMC2973825?pdf=render |
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