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Limiting the Persistence of a Chromosome Break Diminishes Its Mutagenic Potential
To characterize the repair pathways of chromosome double-strand breaks (DSBs), one approach involves monitoring the repair of site-specific DSBs generated by rare-cutting endonucleases, such as I-SceI. Using this method, we first describe the roles of Ercc1, Msh2, Nbs1, Xrcc4, and Brca1 in a set of...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752804/ https://ncbi.nlm.nih.gov/pubmed/19834534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000683 |
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