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Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair

Characterizing the functional overlap and mutagenic potential of different pathways of chromosomal double-strand break (DSB) repair is important to understand how mutations arise during cancer development and treatment. To this end, we have compared the role of individual factors in three different...

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Detalhes bibliográficos
Main Authors: Bennardo, Nicole, Cheng, Anita, Huang, Nick, Stark, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430616/
https://ncbi.nlm.nih.gov/pubmed/18584027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000110
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