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PATHWAYS FOR DOUBLE-STRAND BREAK REPAIR IN GENETICALLY UNSTABLE Z-DNA-FORMING SEQUENCES
DNA can adopt many structures that differ from the canonical B-form, and several of these non-canonical DNA structures have been implicated in genetic instability associated with human disease. Previously, we found that Z-DNA causes DNA double-strand breaks (DSBs) in mammalian cells that can result...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878134/ https://ncbi.nlm.nih.gov/pubmed/20347845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.035 |
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