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PATHWAYS FOR DOUBLE-STRAND BREAK REPAIR IN GENETICALLY UNSTABLE Z-DNA-FORMING SEQUENCES

DNA can adopt many structures that differ from the canonical B-form, and several of these non-canonical DNA structures have been implicated in genetic instability associated with human disease. Previously, we found that Z-DNA causes DNA double-strand breaks (DSBs) in mammalian cells that can result...

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Bibliografiska uppgifter
Huvudupphovsmän: Kha, Diem T., Wang, Guliang, Natrajan, Nithya, Harrison, Lynn, Vasquez, Karen M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878134/
https://ncbi.nlm.nih.gov/pubmed/20347845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.035
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