Secondary structure forming sequences drive SD-MMEJ repair of DNA double-strand breaks

Alternative end-joining (alt-EJ) repair of DNA double-strand breaks is associated with deletions, chromosome translocations, and genome instability. Alt-EJ frequently uses annealing of microhomologous sequences to tether broken ends. When accessible pre-existing microhomologies do not exist, we have...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Khodaverdian, Varandt Y., Hanscom, Terrence, Yu, Amy Marie, Yu, Taylor L., Mak, Victoria, Brown, Alexander J., Roberts, Steven A., McVey, Mitch
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Genome Integrity, Repair and Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5728401/
https://ncbi.nlm.nih.gov/pubmed/29121353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1056
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky