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Z-DNA-forming sequences generate large-scale deletions in mammalian cells
Spontaneous chromosomal breakages frequently occur at genomic hot spots in the absence of DNA damage and can result in translocation-related human disease. Chromosomal breakpoints are often mapped near purine–pyrimidine Z-DNA-forming sequences in human tumors. However, it is not known whether Z-DNA...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413824/ https://ncbi.nlm.nih.gov/pubmed/16473937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511084103 |
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