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Z-DNA-forming sequences generate large-scale deletions in mammalian cells

Spontaneous chromosomal breakages frequently occur at genomic hot spots in the absence of DNA damage and can result in translocation-related human disease. Chromosomal breakpoints are often mapped near purine–pyrimidine Z-DNA-forming sequences in human tumors. However, it is not known whether Z-DNA...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Guliang, Christensen, Laura A., Vasquez, Karen M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2006
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413824/
https://ncbi.nlm.nih.gov/pubmed/16473937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511084103
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