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Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells
Naturally occurring DNA sequences can form noncanonical structures such as H-DNA, which are abundant and regulate the expression of several disease-linked genes. Here, we show that H-DNA-forming sequences are intrinsically mutagenic in mammalian cells. This finding suggests that DNA is a causative f...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2004
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC518777/ https://ncbi.nlm.nih.gov/pubmed/15342911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405116101 |
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