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Inhibitory effect of a short Z-DNA forming sequence on transcription elongation by T7 RNA polymerase

DNA sequences capable of forming unusual secondary structures can be a source of genomic instability. In some cases that instability might be affected by transcription, as recently shown for the Z-DNA forming sequence (CG)(14), which causes genomic instability both in mammalian cells and in bacteria...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ditlevson, Jennifer V., Tornaletti, Silvia, Belotserkovskii, Boris P., Teijeiro, Virginia, Wang, Guliang, Vasquez, Karen M., Hanawalt, Philip C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2425487/
https://ncbi.nlm.nih.gov/pubmed/18400779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn136
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