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R-loop generation during transcription: formation, processing and cellular outcomes

R-loops are structures consisting of an RNA-DNA duplex and an unpaired DNA strand. They can form during transcription upon nascent RNA “threadback” invasion into the DNA duplex to displace the non-template strand. Although R-loops occur naturally in all kingdoms of life and serve regulatory roles, t...

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Bibliografische gegevens
Gepubliceerd in:DNA Repair (Amst)
Hoofdauteurs: Belotserkovskii, Boris P., Tornaletti, Silvia, D’Souza, Alicia D., Hanawalt, Philip C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340742/
https://ncbi.nlm.nih.gov/pubmed/30190235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.08.009
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