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R-loop generation during transcription: formation, processing and cellular outcomes
R-loops are structures consisting of an RNA-DNA duplex and an unpaired DNA strand. They can form during transcription upon nascent RNA “threadback” invasion into the DNA duplex to displace the non-template strand. Although R-loops occur naturally in all kingdoms of life and serve regulatory roles, t...
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| 發表在: | DNA Repair (Amst) |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6340742/ https://ncbi.nlm.nih.gov/pubmed/30190235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.08.009 |
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