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R-loop generation during transcription: formation, processing and cellular outcomes
R-loops are structures consisting of an RNA-DNA duplex and an unpaired DNA strand. They can form during transcription upon nascent RNA “threadback” invasion into the DNA duplex to displace the non-template strand. Although R-loops occur naturally in all kingdoms of life and serve regulatory roles, t...
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| Gepubliceerd in: | DNA Repair (Amst) |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6340742/ https://ncbi.nlm.nih.gov/pubmed/30190235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.08.009 |
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