AP-1 (Fra-1/c-Jun)-mediated Induction of Expression of Matrix Metalloproteinase-2 Is Required for 15(S)-Hydroxyeicosatetraenoic Acid-induced Angiogenesis

To understand the involvement of matrix metalloproteinases (MMPs) in 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE)-induced angiogenesis, we have studied the role of MMP-2. 15(S)-HETE induced MMP-2 expression and activity in a time-dependent manner in human dermal microvascular endothelial cells (H...

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Main Authors: Singh, Nikhlesh K., Quyen, Dong Van, Kundumani-Sridharan, Venkatesh, Brooks, Peter C., Rao, Gadiparthi N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878006/
https://ncbi.nlm.nih.gov/pubmed/20353950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106187
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