Acetylation of Lysine 564 Adjacent to the C-terminal Binding Protein-binding Motif in EVI1 Is Crucial for Transcriptional Activation of GATA2

Ecotropic viral integration site 1 (EVI1) is an important transcription factor for leukemogenesis. EVI1 is a member of a group of transcription factors with C-terminal binding protein (CtBP)-binding motifs that act as transcriptional co-repressors; however, we recently found that EVI1 directly activ...

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Detalhes bibliográficos
Main Authors: Shimahara, Akiko, Yamakawa, Norio, Nishikata, Ichiro, Morishita, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878005/
https://ncbi.nlm.nih.gov/pubmed/20363750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.102046
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