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Druggability Analysis and Structural Classification of Bromodomain Acetyl-lysine Binding Sites
[Image: see text] Bromodomains are readers of the epigenetic code that specifically bind acetyl-lysine containing recognition sites on proteins. Recently the BET family of bromodomains has been demonstrated to be druggable through the discovery of potent inhibitors, sparking an interest in protein–p...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3441041/ https://ncbi.nlm.nih.gov/pubmed/22788793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300346w |
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