Acetylation of Lysine 564 Adjacent to the C-terminal Binding Protein-binding Motif in EVI1 Is Crucial for Transcriptional Activation of GATA2

Por Shimahara, Akiko, Yamakawa, Norio, Nishikata, Ichiro, Morishita, Kazuhiro
Publicado em 2010

The Increased Expression of Integrin α6 (ITGA6) Enhances Drug Resistance in EVI1(high) Leukemia

Por Yamakawa, Norio, Kaneda, Kazuko, Saito, Yusuke, Ichihara, Emi, Morishita, Kazuhiro
Publicado em 2012

Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development

Por Ichikawa, Tomonaga, Nakahata, Shingo, Fujii, Masahiro, Iha, Hidekatsu, Morishita, Kazuhiro
Publicado no Sci Rep (2015)

FUNCTION OF ECOTROPIC VIRAL INTEGRATION SITE 1 (EVI1) GENE IN MOUSE NEURAL PRECURSOR CELLS AND HUMAN GLIOMA INITIATING CELLS

Por Takeshima, Hideo, Yokogami, Kiyotaka, Mizuguchi, Asako, Yamasaki, Kouji, Kawasoe, Takuma, Morishita, Kazuhiro
Publicado em 2014

NDRG2 plays a pivotal role in ATLL leukaemogenesis by regulating the PTEN-mediated PI3K/AKT signalling pathway

Por Nakahata, Shingo, Ichikawa, Tomonaga, Saito, Yusuke, Arai, Yasuhito, Taki, Tomohiko, Taniwaki, Masafumi, Morishita, Kazuhiro
Publicado em 2014

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression

Por Yuasa, Hiromi, Oike, Yuichi, Iwama, Atsushi, Nishikata, Ichiro, Sugiyama, Daisuke, Perkins, Archibald, Mucenski, Michael L, Suda, Toshio, Morishita, Kazuhiro
Publicado em 2005

Critical Role for TSLC1 Expression in the Growth and Organ Infiltration of Adult T-Cell Leukemia Cells In Vivo

Por Dewan, M. Zahidunnabi, Takamatsu, Naofumi, Hidaka, Tomonori, Hatakeyama, Kinta, Nakahata, Shingo, Fujisawa, Jun-ichi, Katano, Harutaka, Yamamoto, Naoki, Morishita, Kazuhiro
Publicado em 2008

High resolution lectin microarray system for the ATL cell-typing and the evaluation of anti-cancer efficacy of medications

Por Iha, Hidekatsu, Ikebe, Emi, Matsumoto, Takashi, Nishizono, Akira, Ogata, Masao, Tanaka, Yuetsu, Hori, Mitsuo, Sueoka, Eisaburo, Fujisawa, Jun-ichi, Morishita, Kazuhiro
Publicado em 2014

Superoxide-Generating Nox5α Is Functionally Required for the Human T-Cell Leukemia Virus Type 1-Induced Cell Transformation Phenotype

Por Shigemura, Tomonari, Shiohara, Masaaki, Kato, Masayoshi, Furuta, Shuichi, Kaneda, Kazuko, Morishita, Kazuhiro, Hasegawa, Hiroo, Fujii, Masahiro, Gorlach, Agnes, Koike, Kenichi, Kamata, Tohru
Publicado no J Virol (2015)

Downregulation of CDKN1A in Adult T-Cell Leukemia/Lymphoma despite Overexpression of CDKN1A in Human T-Lymphotropic Virus 1-Infected Cell Lines

Por Watanabe, Masaaki, Nakahata, Shingo, Hamasaki, Makoto, Saito, Yusuke, Kawano, Yohei, Hidaka, Tomonori, Yamashita, Kiyoshi, Umeki, Kazumi, Taki, Tomohiko, Taniwaki, Masafumi, Okayama, Akihiko, Morishita, Kazuhiro
Publicado em 2010

Clinical significance of CADM1/TSLC1/IgSF4 expression in Adult-T cell leukemia/lymphoma (ATLL): identification of various types of ATLL cells

Por Nakahata, Shingo, Saito, Yusuke, Marutsuka, Kosuke, Hidaka, Tomonori, Maeda, Koichi, Utsunomiya, Atae, Okayama, Akihiko, Kubuki, Yoko, Shimoda, Kazuya, Asada, Yujiro, Ukai, Yoshinori, Kuosawa, Gene, Morishita, Kazuhiro
Publicado em 2011

Development of a complete human anti-human transferrin receptor C antibody as a novel marker of oral dysplasia and oral cancer

Por Nagai, Kentaro, Nakahata, Shingo, Shimosaki, Shunsuke, Tamura, Tomohiro, Kondo, Yuudai, Baba, Takashi, Taki, Tomohiko, Taniwaki, Masafumi, Kurosawa, Gene, Sudo, Yukio, Okada, Seiji, Sakoda, Sumio, Morishita, Kazuhiro
Publicado no Cancer Med (2014)

Furin-dependent CCL17-fused recombinant toxin controls HTLV-1 infection by targeting and eliminating infected CCR4-expressing cells in vitro and in vivo

Por Hiyoshi, Masateru, Okuma, Kazu, Tateyama, Seiji, Takizawa, Kazuya, Saito, Masumichi, Kuramitsu, Madoka, Araki, Kumiko, Morishita, Kazuhiro, Okada, Seiji, Yamamoto, Naoki, Biragyn, Arya, Yamaguchi, Kazunari, Hamaguchi, Isao
Publicado no Retrovirology (2015)

miR-133 regulates Evi1 expression in AML cells as a potential therapeutic target

Por Yamamoto, Haruna, Lu, Jun, Oba, Shigeyoshi, Kawamata, Toyotaka, Yoshimi, Akihide, Kurosaki, Natsumi, Yokoyama, Kazuaki, Matsushita, Hiromichi, Kurokawa, Mineo, Tojo, Arinobu, Ando, Kiyoshi, Morishita, Kazuhiro, Katagiri, Koko, Kotani, Ai
Publicado no Sci Rep (2016)

Identification of a Bioactive Compound against Adult T-cell Leukaemia from Bitter Gourd Seeds

Por Kai, Hisahiro, Akamatsu, Ena, Torii, Eri, Kodama, Hiroko, Yukizaki, Chizuko, Akagi, Isao, Ino, Hisatoshi, Sakakibara, Yoichi, Suiko, Masahito, Yamamoto, Ikuo, Okayama, Akihiko, Morishita, Kazuhiro, Kataoka, Hiroaki, Matsuno, Koji
Publicado no Plants (Basel) (2013)

Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers

Por Nakahata, Shingo, Ichikawa, Tomonaga, Maneesaay, Phudit, Saito, Yusuke, Nagai, Kentaro, Tamura, Tomohiro, Manachai, Nawin, Yamakawa, Norio, Hamasaki, Makoto, Kitabayashi, Issay, Arai, Yasuhito, Kanai, Yae, Taki, Tomohiko, Abe, Takaya, Kiyonari, Hiroshi, Shimoda, Kazuya, Ohshima, Koichi, Horii, Akira, Shima, Hiroshi, Taniwaki, Masafumi, Yamaguchi, Ryoji, Morishita, Kazuhiro
Publicado em 2014

A novel HSP90 inhibitor, 17-DMAG, induces Tax down-regulation and its oral administration to ATL-model mice intervenes against the infiltration property of the ATL-like lymphocytes...

Por Ikebe, Emi, Kawaguchi, Akira, Tezuka, Kenta, Taguchi, Shinya, Hirose, Satoshi, Matsumoto, Takashi, Mitsui, Takahiro, Senba, Kazuyo, Nishizono, Akira, Hori, Mitsuo, Hasegawa, Hiroo, Yamada, Yasuaki, Ueno, Takaharu, Tanaka, Yuetsu, Sawa, Hirofumi, Hall, William, Minami, Yasuaki, Jeang, Kuan-Teh, Ogata, Masao, Morishita, Kazuhiro, Hasegawa, Hideki, Fujisawa, Jun-ichi, Iha, Hidekatsu
Publicado em 2014