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Loss of NDRG2 enhanced activation of the NF-κB pathway by PTEN and NIK phosphorylation for ATL and other cancer development

The activation of nuclear factor kappa B (NF-κB) signaling has a central role in the development of adult T-cell leukemia/lymphoma (ATL) and many other cancers. However, the activation mechanism of the NF-κB pathways remains poorly understood. Recently, we reported that N-myc downstream-regulated ge...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ichikawa, Tomonaga, Nakahata, Shingo, Fujii, Masahiro, Iha, Hidekatsu, Morishita, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534796/
https://ncbi.nlm.nih.gov/pubmed/26269411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12841
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