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FUNCTION OF ECOTROPIC VIRAL INTEGRATION SITE 1 (EVI1) GENE IN MOUSE NEURAL PRECURSOR CELLS AND HUMAN GLIOMA INITIATING CELLS

BACKGROUND: Ecotropic viral integration site 1 (EVI1) gene encodes a transcription factor, containing ten zinc finger motifs found within two domains of the protein. Abnormal expression of EVI1 is found in 5-10% of patients with acute myeloid leukemia (AML), and is associated with unfavorable outcom...

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Bibliographische Detailangaben
Hauptverfasser: Takeshima, Hideo, Yokogami, Kiyotaka, Mizuguchi, Asako, Yamasaki, Kouji, Kawasoe, Takuma, Morishita, Kazuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144551/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.80
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