miR-133 regulates Evi1 expression in AML cells as a potential therapeutic target

The Ecotropic viral integration site 1 (Evi1) is a zinc finger transcription factor, which is located on chromosome 3q26, over-expression in some acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Elevated Evi1 expression in AML is associated with unfavorable prognosis. Therefore, Evi1...

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Published in:Sci Rep
Main Authors: Yamamoto, Haruna, Lu, Jun, Oba, Shigeyoshi, Kawamata, Toyotaka, Yoshimi, Akihide, Kurosaki, Natsumi, Yokoyama, Kazuaki, Matsushita, Hiromichi, Kurokawa, Mineo, Tojo, Arinobu, Ando, Kiyoshi, Morishita, Kazuhiro, Katagiri, Koko, Kotani, Ai
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709720/
https://ncbi.nlm.nih.gov/pubmed/26754824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19204
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