Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity

Ecotropic viral integration site 1 (Evi1), a transcription factor of the SET/PR domain protein family, is essential for the maintenance of hematopoietic stem cells (HSCs) in mice and is overexpressed in several myeloid malignancies. Here, we generate reporter mice in which an internal ribosome entry...

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Autors principals: Kataoka, Keisuke, Sato, Tomohiko, Yoshimi, Akihide, Goyama, Susumu, Tsuruta, Takako, Kobayashi, Hiroshi, Shimabe, Munetake, Arai, Shunya, Nakagawa, Masahiro, Imai, Yoichi, Kumano, Keiki, Kumagai, Katsuyoshi, Kubota, Naoto, Kadowaki, Takashi, Kurokawa, Mineo
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256960/
https://ncbi.nlm.nih.gov/pubmed/22084405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110447
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