Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity

Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy that originates from leukemia-initiating cells (LICs). The identification of common mechanisms underlying LIC development will be important in establishing broadly effective therapeutics for AML. Constitutive NF-κB pathway activa...

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Hlavní autoři: Kagoya, Yuki, Yoshimi, Akihide, Kataoka, Keisuke, Nakagawa, Masahiro, Kumano, Keiki, Arai, Shunya, Kobayashi, Hiroshi, Saito, Taku, Iwakura, Yoichiro, Kurokawa, Mineo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904603/
https://ncbi.nlm.nih.gov/pubmed/24382349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68101
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