Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate

Chronic myelomonocytic leukemia (CMML) is an entity of myelodysplastic syndrome/myeloproliferative neoplasm. Although CMML can be cured with allogeneic stem cell transplantation, its prognosis is generally very poor due to the limited efficacy of chemotherapy and to the patient’s age, which is usual...

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Publicado no:Sci Rep
Main Authors: Taoka, Kazuki, Arai, Shunya, Kataoka, Keisuke, Hosoi, Masataka, Miyauchi, Masashi, Yamazaki, Sho, Honda, Akira, Aixinjueluo, Wei, Kobayashi, Takashi, Kumano, Keiki, Yoshimi, Akihide, Otsu, Makoto, Niwa, Akira, Nakahata, Tatsutoshi, Nakauchi, Hiromitsu, Kurokawa, Mineo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203784/
https://ncbi.nlm.nih.gov/pubmed/30367142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34193-1
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