Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity

Ecotropic viral integration site 1 (Evi1), a transcription factor of the SET/PR domain protein family, is essential for the maintenance of hematopoietic stem cells (HSCs) in mice and is overexpressed in several myeloid malignancies. Here, we generate reporter mice in which an internal ribosome entry...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kataoka, Keisuke, Sato, Tomohiko, Yoshimi, Akihide, Goyama, Susumu, Tsuruta, Takako, Kobayashi, Hiroshi, Shimabe, Munetake, Arai, Shunya, Nakagawa, Masahiro, Imai, Yoichi, Kumano, Keiki, Kumagai, Katsuyoshi, Kubota, Naoto, Kadowaki, Takashi, Kurokawa, Mineo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256960/
https://ncbi.nlm.nih.gov/pubmed/22084405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110447
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