Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias.

The chromosomal translocation t(3;21)(q26;q22), which is found in blastic crisis in chronic myelogenous leukemias and myelodysplastic syndrome-derived leukemias, produces AML1/Evi-1 chimeric transcription factor and is thought to play important roles in acute leukemic transformation of hemopoietic s...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Tanaka, T, Mitani, K, Kurokawa, M, Ogawa, S, Tanaka, K, Nishida, J, Yazaki, Y, Shibata, Y, Hirai, H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7739522/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.5.2383
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