Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias.

The chromosomal translocation t(3;21)(q26;q22), which is found in blastic crisis in chronic myelogenous leukemias and myelodysplastic syndrome-derived leukemias, produces AML1/Evi-1 chimeric transcription factor and is thought to play important roles in acute leukemic transformation of hemopoietic s...

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Detalhes bibliográficos
Main Authors: Tanaka, T, Mitani, K, Kurokawa, M, Ogawa, S, Tanaka, K, Nishida, J, Yazaki, Y, Shibata, Y, Hirai, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230467/
https://ncbi.nlm.nih.gov/pubmed/7739522
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