BET Acetyl-Lysine Binding Proteins Control Pathological Cardiac Hypertrophy

Cardiac hypertrophy is an independent predictor of adverse outcomes in patients with heart failure, and thus represents an attractive target for novel therapeutic intervention. JQ1, a small molecule inhibitor of bromodomain and extraterminal (BET) acetyl-lysine reader proteins, was identified in a h...

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Hlavní autoři: Spiltoir, Jessica I., Stratton, Matthew S., Cavasin, Maria A., Demos-Davies, Kim, Reid, Brian G., Qi, Jun, Bradner, James E., McKinsey, Timothy A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089995/
https://ncbi.nlm.nih.gov/pubmed/23939492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.07.017
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