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Discovery of novel small molecule inhibitors of cardiac hypertrophy using high throughput, high content imaging

Chronic cardiac hypertrophy is maladaptive and contributes to the pathogenesis of heart failure. The objective of this study was to identify small molecule inhibitors of pathological cardiomyocyte hypertrophy. High content screening was performed with primary neonatal rat ventricular myocytes (NRVMs...

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Bibliografiske detaljer
Udgivet i:J Mol Cell Cardiol
Main Authors: Reid, Brian G., Stratton, Matthew S., Bowers, Samantha, Cavasin, Maria A., Demos-Davies, Kimberley M., Susano, Isidro, McKinsey, Timothy A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002372/
https://ncbi.nlm.nih.gov/pubmed/27130278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.04.015
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