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Loss of p73 promotes dissemination of Myc-induced B cell lymphomas in mice

Mice engineered to express c-Myc in B cells (Eμ-myc mice) develop lethal lymphomas in which the gene encoding the p53 tumor suppressor is frequently mutated. Whether the p53 homolog p73 also functions as a tumor suppressor in vivo remains controversial. Here we have shown that p73 loss does not subs...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nemajerova, Alice, Petrenko, Oleksi, Trümper, Lorenz, Palacios, Gustavo, Moll, Ute M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877938/
https://ncbi.nlm.nih.gov/pubmed/20484818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40331
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