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Impaired DNA damage checkpoint response in MIF-deficient mice
Recent studies demonstrated that proinflammatory migration inhibitory factor(MIF) blocks p53-dependent apoptosis and interferes with the tumor suppressor activity of p53. To explore the mechanism underlying this MIF-p53 relationship, we studied spontaneous tumorigenesis in genetically matched p53−/−...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852846/ https://ncbi.nlm.nih.gov/pubmed/17290223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601564 |
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