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Loss of p73 promotes dissemination of Myc-induced B cell lymphomas in mice
Mice engineered to express c-Myc in B cells (Eμ-myc mice) develop lethal lymphomas in which the gene encoding the p53 tumor suppressor is frequently mutated. Whether the p53 homolog p73 also functions as a tumor suppressor in vivo remains controversial. Here we have shown that p73 loss does not subs...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877938/ https://ncbi.nlm.nih.gov/pubmed/20484818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40331 |
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