Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice()

BACKGROUND & AIMS: Suppression of the hypothalamic–pituitary–adrenal axis occurs in cirrhosis and cholestasis and is associated with increased concentrations of bile acids. We investigated whether this was mediated through bile acids acting to impair steroid clearance by inhibiting glucocorticoi...

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Main Authors: McNeilly, Alison D., Macfarlane, David P., O’Flaherty, Emmett, Livingstone, Dawn E., Mitić, Tijana, McConnell, Kirsty M., McKenzie, Scott M., Davies, Eleanor, Reynolds, Rebecca M., Thiesson, Helle C., Skøtt, Ole, Walker, Brian R., Andrew, Ruth
格式: Artigo
語言:Inglês
出版: Elsevier 2010
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877801/
https://ncbi.nlm.nih.gov/pubmed/20347173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.10.037
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