Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice()

BACKGROUND & AIMS: Suppression of the hypothalamic–pituitary–adrenal axis occurs in cirrhosis and cholestasis and is associated with increased concentrations of bile acids. We investigated whether this was mediated through bile acids acting to impair steroid clearance by inhibiting glucocorticoi...

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Detalhes bibliográficos
Main Authors: McNeilly, Alison D., Macfarlane, David P., O’Flaherty, Emmett, Livingstone, Dawn E., Mitić, Tijana, McConnell, Kirsty M., McKenzie, Scott M., Davies, Eleanor, Reynolds, Rebecca M., Thiesson, Helle C., Skøtt, Ole, Walker, Brian R., Andrew, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877801/
https://ncbi.nlm.nih.gov/pubmed/20347173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.10.037
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