Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice()

BACKGROUND & AIMS: Suppression of the hypothalamic–pituitary–adrenal axis occurs in cirrhosis and cholestasis and is associated with increased concentrations of bile acids. We investigated whether this was mediated through bile acids acting to impair steroid clearance by inhibiting glucocorticoi...

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Autors principals: McNeilly, Alison D., Macfarlane, David P., O’Flaherty, Emmett, Livingstone, Dawn E., Mitić, Tijana, McConnell, Kirsty M., McKenzie, Scott M., Davies, Eleanor, Reynolds, Rebecca M., Thiesson, Helle C., Skøtt, Ole, Walker, Brian R., Andrew, Ruth
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877801/
https://ncbi.nlm.nih.gov/pubmed/20347173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.10.037
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