Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice()

BACKGROUND & AIMS: Suppression of the hypothalamic–pituitary–adrenal axis occurs in cirrhosis and cholestasis and is associated with increased concentrations of bile acids. We investigated whether this was mediated through bile acids acting to impair steroid clearance by inhibiting glucocorticoi...

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Detaylı Bibliyografya
Asıl Yazarlar: McNeilly, Alison D., Macfarlane, David P., O’Flaherty, Emmett, Livingstone, Dawn E., Mitić, Tijana, McConnell, Kirsty M., McKenzie, Scott M., Davies, Eleanor, Reynolds, Rebecca M., Thiesson, Helle C., Skøtt, Ole, Walker, Brian R., Andrew, Ruth
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877801/
https://ncbi.nlm.nih.gov/pubmed/20347173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.10.037
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