Bile acids modulate glucocorticoid metabolism and the hypothalamic–pituitary–adrenal axis in obstructive jaundice()

BACKGROUND & AIMS: Suppression of the hypothalamic–pituitary–adrenal axis occurs in cirrhosis and cholestasis and is associated with increased concentrations of bile acids. We investigated whether this was mediated through bile acids acting to impair steroid clearance by inhibiting glucocorticoi...

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Autores principales: McNeilly, Alison D., Macfarlane, David P., O’Flaherty, Emmett, Livingstone, Dawn E., Mitić, Tijana, McConnell, Kirsty M., McKenzie, Scott M., Davies, Eleanor, Reynolds, Rebecca M., Thiesson, Helle C., Skøtt, Ole, Walker, Brian R., Andrew, Ruth
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877801/
https://ncbi.nlm.nih.gov/pubmed/20347173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2009.10.037
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